基于WGCNA的马铃薯根系抗旱相关共表达模块鉴定和核心基因发掘
秦天元,孙超,毕真真,梁文君,李鹏程,张俊莲,白江平

Identification of drought-related co-expression modules and hub genes in potato roots based on WGCNA
Tian-Yuan QIN,Chao SUN,Zhen-Zhen BI,Wen-Jun LIANG,Peng-Cheng LI,Jun-Lian ZHANG,Jiang-Ping BAI
表3 不同模块中核心基因的功能注释
Table 3 Functional annotations of hub genes in different modules
模块
Module
核心基因
Hub gene
核心基因在
拟南芥同源基因
Hub gene in A. thaliana
基因功能
Gene function
Red PGSC0003DMG400030368 AT1G07140 编码假定的RAN结合蛋白。
Encodes a putative RAN-binding protein (siRANBP).
Red PGSC0003DMG400003662 AT1G20270; AT5G66060 2-氧戊二酸和铁依赖性加氧酶超家族蛋白; 铁离子结合/氧化还原酶/氧化还原酶蛋白。
2-oxoglutarate and Fe-dependent oxygenase superfamily protein; Ironion binding/oxidoreductase/oxidoreductase protein.
Red PGSC0003DMG402020462 AT5G25360 假设性蛋白质。
Hypothetical protein (source: Araport 11).
Red PGSC0003DMG400005154 X 未知功能。Unknown.
Red PGSC0003DMG400020562 AT2G40470 含LOB结构域的蛋白质。参与木质部分化的调节——作为VND7的调节器, VND7是木质部细胞分化的主要调节器。
LOB-domain containing protein. Involved in regulation of xylem differentiation—acts as a regulator of VND7 which is a master regulator of xylem cell differentiation.
Yellow PGSC0003DMG400029350 AT1G05680[15] 编码一个UDP-葡萄糖基转移酶, ugt74e2, 作用于IBA (吲哚-3-丁酸)并影响生长素的稳态。这种酶的转录和蛋白质水平被H2O2强烈诱导, 可能允许ROS (活性氧物种)和生长素信号的整合。
Encodes a UDP-glucosyltransferase, ugt74e2, that acts on IBA (indole-3-butyric acid) and affects auxin homeostasis. The transcript and protein levels of this enzyme are strongly induced by H2O2 and mayallow integration of ROS (reactive oxygen species) and auxin signaling.
Yellow PGSC0003DMG400024717 AT3G05545 超家族蛋白。
RING/U-box superfamily protein (source: Araport 11).
Yellow PGSC0003DMG400026572 AT3G51730[16] 含皂苷B结构域的蛋白质。
Saposin B domain-containing protein (source: Araport 11).
Yellow PGSC0003DMG400006704 AT5G35200[17] 超家族蛋白。
ENTH/ANTH/VHS superfamily protein (source: Araport 11).
Yellow PGSC0003DMG400015386 AT2G42610 光依赖性短下胚轴样蛋白。
LIGHT-DEPENDENT SHORT HYPOCOTYLS-like protein (DUF640) (source: Araport 11).
Yellow PGSC0003DMG400026238 AT3G60410 假设性蛋白质。
Hypothetical protein (DUF1639) (source: Araport 11).
模块
Module
核心基因
Hub gene
核心基因在
拟南芥同源基因
Hub gene in A. thaliana
基因功能
Gene function
Yellow PGSC0003DMG400020683 AT3G25910 MAP激酶
Mitogen-activated protein kinases (DUF1644)(source: Araport 11).
Yellow PGSC0003DMG400024687 AT1G55000[18] 含蛋白的肽聚糖结合赖氨酸域。
Peptidoglycan-binding LysM domain-containing protein (source: Araport 11).
Yellow PGSC0003DMG400006516 AT1G55570 SKU5 similar 12 (source: Araport 11).
Turquoise PGSC0003DMG400013391 AT3G22990 含有蛋白质的犰狳重复序列, 位于核内, 广泛表达于植物。
Armadillo-repeat containing protein, located in nucleus, broadly expressed throughout vegetative.
Turquoise PGSC0003DMG400003792 AT3G14110[19] 编码一种新的盘绕线圈, 含有TPR结构域的蛋白质, 定位于叶绿体膜并参与叶绿素的生物合成。
Encodes a novel coiled-coil, TPR domain containing protein that is localized to the chloroplast membrane and is involved in chlorophyll biosynthesis.
Turquoise PGSC0003DMG400024698 AT5G27620 核心细胞周期基因的mRNA是细胞间流动的。
Core cell cycle genes the mRNA is cell-to-cell mobile.
Turquoise PGSC0003DMG402011550 AT5G23200 C5orf35 (source: Araport 11).
Blue PGSC0003DMG400018372 X 未知功能。Unknown.
Blue PGSC0003DMG400026187 AT3G50950 编码一种典型的CC型NLR蛋白, 该蛋白是识别病原菌丁香中T3SE-Hopz1a所必需的。
Encodes a canonical CC-type NLR protein that is required for the recognition of the T3SE HopZ1a from the pathogenic bacteria P. syringae