%A CHENGWei,LIHe-Ping,HEShui-Lin,LIAOYu-Cai %T Progress in Enhancement of Plant Resistance against Fungal Diseases through Host-Induced Gene Silencing %0 Journal Article %D 2017 %J Acta Agronomica Sinica %R 10.3724/SP.J.1006.2017.01115 %P 1115-1121 %V 43 %N 08 %U {https://zwxb.chinacrops.org/CN/abstract/article_6321.shtml} %8 2017-08-12 %X

Host-induced gene silencing (HIGS) uses the key genes that are involved in growth and development, sporulation and propagation, and pathogenesis of pathogens as targets, and expresses the RNAi constructs in host plants targeting to the target genes; during infection of plants, pathogens take up dsRNA or siRNA molecules, specifically bind to nucleotide sequences after recognition, and interfere the expression of the target genes, thereby inhibiting infection and spreading of invaded pathogens and thus conferring resistance phenotypes in plants. This technology serves as the solid foundation of plant resistance based on pathogen-specific sequences and has great potential for application in crop improvement against fungal diseases. In this review, recent advances in methodologies, technological routes and application of the HIGS strategy in plants against invading fungal pathogens are summarized; prospects for the future in HIGS-based plant resistance to fungal pathogens were also discussed.