作物学报 ›› 2012, Vol. 38 ›› Issue (01): 1-9.doi: 10.3724/SP.J.1006.2012.00001
• 综述 • 下一篇
王后苗,廖伯寿*
WANG Hou-Miao,LIAO Bo-Shou*
摘要: 黄曲霉毒素(aflatoxin,AFT)是曲霉属真菌产生的一大类生物毒素,是危及食品安全和人类健康的主要物质之一。农产品收获前黄曲霉毒素污染是热带、亚热带地区普遍存在的问题,其中在玉米、花生、棉籽、辣椒籽和一些木本坚果及其产品中尤为严重。国内外现有研究结果表明,多种因素可影响作物收获前黄曲霉毒素污染,其中干旱和高温的综合胁迫是最主要的环境因素。作物抗性对降低毒素污染具有重要作用。综合运用分子生物学及常规育种技术改良作物品种对黄曲霉菌侵染或产毒的抗性以及对其他病虫害及干旱的抗(耐)性,是解决黄曲霉毒素污染问题的重要途径。作物生产过程中病虫害的防治和合理的田间管理是作物收获前黄曲霉毒素污染的有效防控措施。
[1]CAST. Mycotoxins: risk in plant, animal, and human systems. In: Richard J L, Payne G A, eds. Council for Agricultural Science and Technology. Task Force Report, Ames, Iowa, No. 139, 2003. p 199 [2]Pohland A E. Mycotoxins in review. Food Add Contam, 1993, 10: 17-28 [3]Bryden W L. Mycotoxins in the food chain: human health implications. Asia Pacific J Clin Nutr. 2007, 16(suppl-1): 95-101 [4]David L E, Evan P G. Mechanisms of aflatoxin carcinogenesis carcinogenesis. Annu Rev Pharmacol Toxicol, 1994, 34: 35-72 [5]John L R. Some major mycotoxins and their mycotoxicoses—An overview. Int J Food Microbiol, 2007, 119: 3-10 [6]Merletti F, Heseltine E, Saracci R, Simonato L, Vainio H, Wilbourn J. Target organs for carcinogenicity of chemicals and industrial exposures in humans: a review of results in the IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans. Cancer Res, 1984, 2244-2250 [7]He L-H(贺立红), Bin J-H(宾金华). Advance on control of peanut aflatoxin contamination. Seed (种子), 2004, 23(12): 39-45 (in Chinese) [8]Liu F-X(刘付香), Li L(李玲), Liang X-Q(梁炫强). Advances on biological control of aflatoxin contamination. Chin J Biol Control (中国生物防治学报), 2010, 26(1): 96-101 (in Chinese with English abstract) [9]Feng J-L(冯建蕾). The hazards of aflatoxin and management. China Anim Hus Veter (中国畜牧兽医), 2005, 32(12): G5-G7 (in Chinese) [10]Flora O, Manjula K, Ranajit B, Tope O, Kayode BA. Bio-detoxification of aflatoxin B1 in artificially contaminated maize grains using lactic acid bacteria. Toxin Rev, 2010, 29: 115-122 [11]Wang J S, Huang T R, Su J J, Liang F, Wei Z L, Liang Y Q, Luo H T, Kuang S Y, Qian G S, Sun G J, He X, Thomas W K, Qian G S. Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, Peoples Republic of China. Cancer Epidemiol Biomark Prevent. 2001, 10: 143-146 [12]Wild C P, Hall A J. Primary prevention of hepatocellular carcinoma in developing countries. Mutat Res, 2000, 462: 381-393 [13]Payne G A, Brown M P. Genetics and physiology of aflatoxin biosynthesis. Annu Rev Phytopathol, 1998, 36: 329-362 [14]Truckses M W, Dombrink-Kurtzman M A, Tournast V H, White K D. Occurrence of aflatoxins and fumonisins in lncaparina from Guatemala. Food Add Contam, 2002, 19: 671-675 [15]Pang X-G(庞兴国), Ding L-X(丁雷霞), Jing J(姜军), Chen C-F(陈长法). Investigation of peanut aflatoxin contamination in Qingdao. Inspect Quarant Sci(检验检疫科学), 2008, (2): 64-65 (in Chinese) [16]Yu Q-F(郁庆福). Modern Sanitary Microbiology (现代卫生微生物学). Beijing: People Sanitary Press. 1995, pp 241-247 (in Chinese) [17]Sun D-R(孙大容). Peanut Breeding (花生育种学). Beijing: China Agriculture Press. 1998 (in Chinese) [18]Liao B-S(廖伯寿). High Yield and Quality Farming Techniques in China Series—Peanut (中国种植业优质高产技术丛书——花生). Wuhan: Hubei Science and Technology Press, 2003 (in Chinese) [19]Yu J. Genetics and biochemistry of mycotoxin synthesis. In: Arora D K ed. Fungal Biotechnology in Agricultural, Food, and Environmental Applications. New York: Marcel Dekker 2004, Vol. 21, pp. 343-361 [20]Yu J, Cleveland T E, Nierman W C, Bennett J W. Aspergillus flavus genomics: gateway to human and animal health, food safety and crop resistance to diseases. Micrology, 2005, 22: 194-202 [21]Minto R E, Townsend C A. Enzymology and molecular biology of aflatoxin biosynthesis. Chem Rev, 1997, 97: 2537-2555 [22]Payne G A. Process of contamination by aflatoxin producing fungi and their impacts on crops. In: Sinha K K, Bhatnagar D, eds. Mycotoxins in Agriculture and Food Safety. Marcel Dekker, New York, 1998. pp. 279-306 [23]Gary L W, Paul W, Leigh K H, Thomas D B. Effect of Aspergillus flavus inoculation methods and environmental conditions on aflatoxin accumulation in corn hybrids. Toxin Rev, 2009, 28: 70-78 [24]Widstrom N W, Guo B Z, Wilson D M. Integration of crop management and genetics for control of preharvest aflatoxin contamination of corn. J Toxicol Toxin Rev, 2003, 22: 195-223 [25]Hicks J K, Yu J H, Keller N P, Adams T H. Aspergillus sporulation and mycotoxin production both require inactivation of the FadA G alpha protein-dependent signaling pathway. Eur Mol Biol Organization, 1997, 16: 4916-4923 [26]Mehan V K, McDonald D. Screening for resistance to Aspergillus flavus invasion and aflatoxin production in groundnuts. In: ICRISAT Groundnut Improvement Program Occasional, Paper-2, 1980. pp 1-15 [27]Cole R J, Sanders T H, Hill R A, Blankenship P D. Mean geocarposphere temperatures that induce preharvest aflatoxin contamination of peanuts under drought stress. Mycopathologia, 1985, 91: 41-46 [28]McMillian W W, Wilson D M, Widstrom N W. Aflatoxin contamination of preharvest corn in Georgia: a six-year study of insect damage and visible Aspergillus flavus. Environ Qual, 1985, 14: 200-202 [29]Abbas H K, Williams W P, Windham G L, Pringle H C III, Xie W, Shier W T. Aflatoxin and fumonisin contamination of commercial corn (Zea mays) hybrids in Mississippi. Agric Food Chem, 2002, 50: 5246-5254 [30]Zheng Y-P(郑亚萍), Wang C-B(王才斌). Recent progress on aflatoxin contamination of peanut before harvest. Chin Agric Sci Bull (中国农学通报). 1993, 9(5): 11-13 (in Chinese with English abstract) [31]Hill R A, Blankenship P D, Cole R J, Sanders T H. Effectors of soil moisture and temperature on preharvest invasion of peanuts by the Aspergillus flavus group and subsequent aflatoxin development. Appl Environ Microbiol, 1983, 45: 628-633 [32]Li C J, Zhang F S ed. Plant nutrition for food security, human health and environmental protection. In: Proceedings of the 15th International Plant Nutrition Colloquium. Beijing: Tsinghua University Press, 2005 [33]Widstrom N W, Butron A, Guo B Z, Wilson D M, Snook M E, Cleveland T E, Lynch R E. Control of preharvest aflatoxin contamination in maize by pyramiding QTL involved in resistance to ear-feeding insects and invasion by Aspergillus spp. Eur J Agron, 2003, 19: 563-572 [34]Khlangwiset P, Shephard G S, Wu F. Aflatoxins and growth impairment. J Toxicol Toxin Rev, 2011, 30: 175-193 [35]Yu Z-W(于振文). Crop Cultivation (The northern China edition)(作物栽培学各论-北方本). Beijing: China Agriculture Press. 2005, pp 311-312 (in Chinese) [36]Wang L-L(王伶俐), Wang C-X(王翠霞), Zhao C-X(赵春香). Contamination of aflatoxin in peanut and its prevention methods. Jilin Agric (吉林农业). 2010, 4: 113 (in Chinese) [37]Widstrom NW, Wilson D M, Richard J L, McMillian W W. Resistance in maize to preharvest contamination by aflatoxin. Plant Pathol, 1993, 1: 49-54 [38]Zhang J-C(张建成), Jing L(江晨), Li S-L(李双玲), Yang W-Q(杨伟强), Wang C-B(王才斌), Shan S-H(单世华). The condition of aflatoxin contamination and control technology of peanut. Crops (作物杂志), 2006, (1): 67-68 (in Chinese) [39]Xu X-J(徐秀娟). Disease, Pest, Weeds and Rat Harm of Peanut in China (中国花生病虫草鼠害). Beijing: China Agriculture Press (in Chinese) [40]Li H, Butron A, Jiang T, Guo B Z, Coy A E, Lee R D, Widstrom N W, Lynch R E. Evaluation of corn germplasm tolerance to drought stress and effects on aflatoxin production. In: Robens J, Cary J W, Campbell B C, eds. Proceedings of Aflatoxin/Fumonisin Workshop, 2000, Vol. 161, pp 25-27 [41]Wynne J C, Beute M K. Breeding for disease resistance in peanut (Arachis hypogaea L.). Annu Rev Phytopathol, 1991, 29: 279-303 [42]Holbrook C C, Wilson D M, Matheron M E, Anderson W F. Peanut breeding and genetic resources. Plant Breed Rev, 2003, 22: 297-356 [43]Xu J(徐进), Luo X-Y(罗雪云). Molecular biology of aflatoxin biosynthesis. J Hygiene Res (卫生研究), 2003, 32(6): 628-631 (in Chinese with English abstract) [44]Wang S-J(王守经), Zhu Q-J(祝清俊), Hu P(胡鹏), Wang W-M(王未名), Zhang Q-Z(张奇志), Du F-L(杜方岭). Contamination of aflatoxin in peanut and peanut-products and its prevention methods. Food Nutr China (中国食物与营养), 2010, (3): 14-16 (in Chinese with English abstract) [45]Holbrook C C, Guo B Z, Wilson D M, Timper P. The U.S. breeding program to develop peanut with drought tolerance and reduced aflatoxin contamination. Peanut Sci, 2009, 36: 50-53 [46]Hu Q-B(胡琼波). Research advance of occurrence and control of underground pest grub in China. Hubei Agric Sci (湖北农业科学). 2004, (6): 87-92 (in Chinese with English abstract) [47]Guo B Z, Widstrom N W, Cleveland T E, Lynch R E. Control of preharvest aflatoxin contamination in corn: fungus-plant-insect interactions and control strategies. Recent Rese Devel, 2000, 4: 165-176 [48]Lei Y(雷永), Wang S-Y(王圣玉), Li D(李栋), Jiang H-F(姜慧芳), Liao B-S(廖伯寿). Evaluation of resistance to aflatoxin production among peanut germplasm with resistance to bacterial wilt. Chin J Oil Crop Sci (中国油料作物学报), 2004, 26(1): 69-71 (in Chinese with English abstract) [49]Holbrook C C, Kvien C K, Ruckers K S, Wilson D M, Hook J E. Preharvest aflatoxin contamination in drought tolerant and intolerant peanut genotypes. Peanut Sci, 2000, 27: 45-48 [50]Guo B Z, Holbrook C C, Yu J, Lee R D, Lynch R E. Application of technology of gene expression in response to drought stress and elimination of preharvest aflatoxin contamination. In: Abbas H K ed. Aflatoxin and Food Safety, CRC Press, 2006. pp 313-331 [51]Widstrom N W, McMillian W W, Wilson D M. Segregation for resistance to aflatoxin contamination among seeds on an ear of hybrid maize. Crop Sci, 1998, 27: 961-963 [52]Campbell K W, White D G. Evaluation of corn genotypes for resistance to Aspergillus ear rot, kernel infection and aflatoxin production. Plant Dis, 1995, 79: 1039-1045 [53]Brown R L, Chen Z Y, Cleveland T E, Russin J S. Advances in the development of host resistance to aflatoxin contamination by Aspergillus flavus. Phytopathology, 1999, 89: 113-117 [54]olbrook C C, Wilson D M, Matheron M E, Anderson W F. Aspergillus colonization and aflatoxin contamination in peanut genotypes with resistance to other fungal pathogens. Plant Dis, 1997, 81: 1429-1431 [55]Burow M D, Selvaraj M G, Upadhyaya H, Ozias-Akins P, Guo B, Bertioli D J. Genomics of peanut, a major source of oil and protein. In: Moore P H, Ming R, eds. Genomics of Tropical Crop Plants, 2008. pp 421-440 [56]Tian L-R(田立荣), Liao B-S(廖伯寿), Wang S-Y(王圣玉), Lei Y(雷永), Yan L-Y(晏立英), Huang J-Q(黄家权), Li D(李栋), Ren X-P(任小平), Xiao Y(肖洋). Evaluation of resistance to aflatoxin formation in peanut RILs. Chin J Oil Crop Sci (中国油料作物学报). 2009, 31(4): 455-459 (in Chinese with English abstract) [57]Tian L-R(田立荣). Potential of Recombing Resistance to Aflatoxin Production and Resistance Mechnasim in Peanut (Arachis hypogaea L.). Master Thesis of Chinese Academy of Agricultural Sciences, 2009 (in Chinese with English abstract) [58]Deng D-X(邓德祥), Gai J-Y(盖钧镒), Qin T-C(秦泰辰), Bian Y-L(卞云龙), Yin Z-T(印志同), Xu M-L(徐明亮). Genetic control of the resistance to Aspergillus flavus in maize. Acta Agron Sin (作物学报). 2000, 26(6): 731-736 (in Chinese with English abstract) [59]Wang J-K(王建康), Gai J-Y(盖钧镒). Identification of major gene and polygene mixed inheritance model and estimation of genetic parameters of a quantitative trait from F2 progeny. Acta Genet Sin (遗传学报), 1997, 24(5): 432-440 (in Chinese with English abstract) [60]Zhang Y. Genetics of resistance to kernel infection by Aspergillus flavus in maize. Plant Breed, 1997, 116: 146-152 [61]Menkir A, Brown R L, Bandyopadhyay R, Chen Z Y, Cleveland T E. A USA-Africa collaborative strategy for identifying, characterizing, and developing maize germplasm with resistance to aflatoxin contamination. Mycopathologia, 2006, 162: 225-232 [62]Brown R L, Chen Z Y, Menkir A, Cleveland T E, Cardwell K, Kling J. Resistance to aflatoxin accumulation in kernels of maize inbreds selected for ear rot resistance in West and Central Africa. Food Protect, 2001, 64: 396-400 [63]Mixon A C. Developing groundnut lines with resistance to seed colonization by toxin—producing strains of Aspergillus flavus species. Pest Actic News Summ, 1979, 25: 394-400 [64]Zhou G-Y(周桂元), Liang X-Q(梁炫强). The study on genetic control of resistance to infection by the fungus Aspergillus flavus in peanut. J Peanut Sci (花生学报), 2001, 30(3): 13-16 (in Chinese with English abstract) [65]Zhou G-Y(周桂元), Liang X-Q(梁炫强). Analysis of major-minor genes conferring resistance to infection by Aspergillus flavus in peanut. J Peanut Sci (花生学报), 2002, 31(3): 11-14 (in Chinese with English abstract) [66]McMillian W W, Widstrom N W, Wilson D M. Registration of GTMAS:gk maize germplasm. Crop Sci, 1993, 33: 882 [67]Williams W P, Windham G L. Registration of maize germplasm line Mp715. Crop Sci, 2001, 41: 1374-1375 [68]Guo B Z, Widstrom N W, Lee R D, Coy A E, Lynch R E. Registration of maize germplasm GT601 (AM-1) and GT602 (AM-2). Plant Regul, 2007, 1: 153-154 [69]Guo B Z, Chen Z Y, Dewey L R, Scully B T. Drought stress and preharvest aflatoxin contamination in agricultural commodity: genetics, genomics and proteomics. J Integr Plant Biol, 2008, 50: 1281-1291 [70]Liao B S, Zhuang W J, Tang R H, Zhang X Y, Shan S H, Jiang H F, Huang J Q. Peanut aflatoxin and genomics research in China: progress and perspectives. Peanut Sci, 2009, 36: 21-28 [71]Li H-L(黎穗临), Liang X-Q(梁炫强), Li Y-C(李一聪), Zhou G-Y(周桂元), Li S-X(李少雄). Screening of foreign groundnut germplasm for resistance to Aspergillus flavus. Peanut Sci Technol (花生科技), 1999, (4): 25-26 (in Chinese with English abstract) [72]Li H-L(黎穗临). The function of resistance to aflatoxin formation in peanut germplasm. J Peanut Sci (花生学报), 2003, 32: 149-154 (in Chinese with English abstract) [73]Brown R L, Kang M S, Magari R. Determination of resistance to aflatoxin production in maize kernels and detection of fungal colonization using an Aspergillus flavus transformation expressing Escherichia coli β-glucuronidase. Phytopathology, 1995, 85: 983-989 [74]Campbell K W, White D G. Evaluation of corn genotypes for resistance to Aspergillus ear rot, kernel infection, and aflatoxin production. Plant Dis, 1995, 9: 1039-1045 [75]Gardner C A, Darrah L L, Zuber M S, Wallin J R. Genetic control of aflatoxin production in maize. Plant Dis, 1987, 71: 426-429 [76]King S B, Scott G E. Field inoculation techniques to evaluate for reaction to kernel infection by Aspergillus flavus. Phytopathology, 1982, 72: 782-785 [77]Scott GE and Zummo N. Sources of resistance in maize to kernel infection by Aspergillus flavus in the field. Crop Sci, 1988, 28: 504-507 [78]Widstrom N W, McMillian W W, Wilson D M. Segregation for resistance to aflatoxin contamination among seeds on an ear of hybrid maize. Crop Sci, 1987, 27: 961-963 [79]Palanisami A. Fungus aflatoxin producing in relation to post harvest practices in groundnut. Madrea Agric J, 1990, 77: 26-31 [80]Liang X-Q(梁炫强). Studies on the Mechanism and Inheritance of Resistance to Aspergillus flavus Link Invasion and Aflatoxin Production in Peanut. PhD Dissertation of Huanan Normal University, 2002 (in Chinese with English abstract) [81]Fajardo J E. Phenolic compounds in peanut seed enhanced elicitation by chitosan and effects of growth and aflatoxin B1 producing by Aspergillus flavus. Food Biotechnol, 1994, 8: 191-211 [82]Amaya F J, Young C T, Norden A J. Chemical screening for Aspergillus flavus resistance in peanut. Oleagineux, 1990, 35: 255-259 [83]Woloshuk C P, Cavaletto J R, Cleveland T E. Inducers of aflatoxin biosynthesis from colonized maize kernels are generated by an amylase activity from Aspergillus flavus. Phytopathology, 1997, 87: 164-169 [84]Chen Z Y, Brown R L, Lax A R, Cleveland T E, Russin J S. Inhibition of plant pathogenic fungi by a corn trypsin inhibitor overexpressed in Escherichia coli. Appl Environ Microbiol, 1999, 65: 1320-1324 [85]Chen Z Y, Brown R L, Lax A R, Guo B Z, Cleveland T E, Russin JS . Resistance to Aspergillus flavus in corn kernels is associated with a 14 kDa protein. Phytopathology, 1998, 88: 276-281 [86]Chen Z Y, Brown R L, Cleveland T E, Damann K E, Russin J S. Comparison of constitutive and inducible maize kernel proteins of genotypes resistant or susceptible to aflatoxin production. Food Protect, 2001, 64: 1785-1792 [87]Chen Z Y, Brown R L, Damann K E, Cleveland T E. Identification of unique or elevated levels of kernel proteins in aflatoxin-resistant maize genotypes through proteome analysis. Phytopathology, 2002, 92: 1084-1094 [88]Chen Z Y, Brown R L, Damann K E, Cleveland T E. Identification of maize kernel endosperm proteins associated with resistance to aflatoxin contamination by Aspergillus flavus. Phytopathology, 2007, 97: 1094-1103 [89]Chen Z Y, Brown R L, Rajasekaran K, Damann K E, Cleveland T E. Identification of a maize kernel pathogenesis-related protein and evidence for its involvement in resistance to Aspergillus flavus infection and aflatoxin production. Phytopathology, 2006, 96: 87-95 [90]Chen Z Y, Brown R L, Lax A R, Cleveland T E, Russin J S. Identifying aflatoxin resistance-related proteins/genes through proteomics and RNAi gene silencing. Peanut Sci, 2009, 36: 35-41 [91]Yu J, Payne G A, Campbell B C, Guo B Z, Cleveland T E, Robens J F, Keller N P, Bennett J W, Nierman W C. Mycotoxin production and prevention of aflatoxin contamination in food and feed. In: Osmani S, Goldman G, eds. The ASPERGILLI: Genomics, Medical Aspects, Biotechnology, and Research Methods, Boca Raton, FL: CRC Press, 2008. pp. 457-472 |
[1] | 陈丽娜,方沩,司海平,曹永生. 农作物种质资源本体构建研究[J]. 作物学报, 2016, 42(03): 407-414. |
[2] | 王关林;邢卓;潘凌子;方宏筠. 蜂毒肽对农作物生理指标及防御系统酶影响的研究[J]. 作物学报, 2006, 32(04): 593-596. |
[3] | 曹永生;张贤珍;白建军;龚高法. 中国主要粮食作物野生种质资源地理分布[J]. 作物学报, 1999, 25(04): 424-432. |
|