In order to investigate the grain yield and nutrient absorption of modern summer maize varieties in the Yellow-Huaihe- Haihe Rivers region, with the aim at proposing the theoretical basis for rational application of fertilizer, and high yield and high efficiency production, the experiment was conducted in 2016 at National Demonstration Center for New Crop Varieties in Shanghe, Jinan and the State Key Laboratory of Crop Biology, Shandong Agricultural University in Tai’an. Plants were sampled at maturity stage, and the grain yield, yield components, and mineral element uptake and utilization of plants were analyzed. Exploring analyses and normality tests showed that yield per plant, biomass per plant, 1000-kernel weight and grain yield were all conformed to normal distribution, with N (167.0, 22.72 2), N (285.0, 33.47 2), N (318.0, 35.75 2), and N (10.9, 1.50 2), ranging from 141.55 to 246.99 g plant -1, from 197.68 to 389.92 g plant -1, from 226.58 to 413.76 g 1000 kernel -1, and from 5.84 to 13.41 t hm -2, respectively. The average N requirement per 100 kg grain was 1.95 kg and declined with increasing grain yield. When the yield increased from < 7.0 t hm -2 to 8.0-9.0 t hm -2, the N requirement per 100 kg grain decreased from 2.15 to 1.96 kg due to increasing harvest index and decreasing grain N concentration. When the yield increased from 8.0-9.0 t hm -2 to 9.0-11.0 t hm -2, the N requirement per 100 kg grain decreased from 1.96 to 1.84 kg due to decreasing grain N concentration. When the yield was more than 11.0 t hm -2, the N requirement per 100 kg grain tended to be stable. The average P requirement per 100 kg grain was 0.97 kg, which was negatively correlated with grain yield, and declined from 1.07 to 0.92 kg when the yield increased from < 7.0 t hm -2 to > 11.0 t hm -2 due to increasing harvest index and declining grain P concentrations. The average K requirement per 100 kg grain was 1.89 kg, which was negatively correlated with grain yield, showing a decrease from 2.14 to 1.74 kg when the yield increased from < 7.0 t hm -2 to > 11.0 t hm -2, which was attributed to the increase of the harvest index and stem potassium concentrations, and the decline in leaf potassium concentrations. The grain yield of main maize varieties currently grown in the Yellow- Huaihe-Haihe Rivers region was (8.91±1.23) t hm -2, with the N, P2O5, and K2O requirement per 100 kg grain of (1.95±0.24), (0.97±0.11), and (1.89±0.28) kg, respectively. The N, P, and K requirement for plant growth increased with increasing grain yield, while the average N, P2O5 and K2O requirement for producing 100 kg grain declined with increasing grain yield.